The 2025 college football season continues into Week 11 with three Top 25 matchups on Nov. 8 from the recently released College Football Playoff Selection Committem Rankings.
Check out the leading conference contenders, College Football Playoff odds and biggest games games to watch and wager on in the closing weeks of the college football season with four undefeated teams reamining into Week 11 - Ohio State, Indiana, Texas A&M and Brigham Young (BYU).
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No. 19 Southern Cal (USC) kicks off the Top 25 action on Friday night as a 14-point favorite in a Big Ten battle versus Northwestern ahead of the most watched and wagered games on Saturday, Nov. 8.
Top 25 Games and Week 11 Odds
Betting lines and college football odds from BetOnline and top online sportsbooks refresh periodically and are subject to change, including on props and live betting. Current point spread on favorites, plus game totals and updated as of Friday, Nov. 8. All times ET. Top 25 matchups in bold.
Sat., Nov. 8
- No. 1 Ohio State (-29.5) at Purdue, 48 | 1 pm | Big Ten Network
- No. 2 Indiana (-14.5) at Penn State, 50 | 12 pm | FOX
- No. 3 Texas A&M (-7) at No. 22 Missouri, 48.5 | 3:30 pm | ABC
- No. 4 Alabama (-10.5) vs. LSU, 49.5 | 7:30 pm | ABC
- No. 5 Georgia (-9.5) at Mississippi State, 56 | 12 pm | ESPN - No. 6 Ole Miss vs The Citadel | 1 pm | SECN+
- No. 7 BYU at No. 8 Texas Tech (-11), 51.5 | 12 pm | ABC -
- No. 9 Oregon (-6.5) at No. 20 Iowa, 41.5 | 3:30 pm | CBS
- No. 10 Notre Dame (-27.5) vs. Navy, 55 | 12 pm NBC/Peacock
- No. 11 Texas | Bye
- No. 12 Oklahoma | Bye
- No. 13 Utah | Bye
- No. 14 Virginia (-7) vs. Wake Forest, 48 | 7 pm | ESPN
- No. 15 Louisville (-20.5) vs. Cal, 50.5 | ESPN2
- No. 16 Vanderbilt (-6.5) vs. Auburn, 45 | 7 pm | SECN
- No. 17 Georgia Tech | Bye
- No. 18 Miami (-28.5) vs. Syracuse, 46 | 3:30 pm | ESPN
- No. 21 Michigan | Bye
- No. 23 Washington (-11) at Wisconsin, 44 | 7:30 pm | Big Ten Network
- No. 24 Pittsburgh | Bye
- No. 25 Tennessee | Bye
Some line changes of note since early week include Indiana from -15 to 14.5 and total 48.5 to 50. Georgia is up from -7.5 to -9.5 and total down 57.5 to 56. Notre Dame -26.5 to -27.5, Ohio State/Purdue total 49.5 to 48 and Washington/Wisconsin total 45.5 to 44. Top 25 matchups Texas Tech -10 to -11, Oregon -6 to -6.5 and total 40.5 to 41.5.
Other notable games on Sat., Nov. 8
- Florida State at Clemson (-1), 56
- Duke (-8.5) at Connecticut, 63.5
- Iowa State at TCU (-7.5), 56.5
- Tulane at Memphis (-4.5), 55
- Wake Forest at Virginia (-6.5), 48
- San Diego State (-7) at Hawaii, 48.5
NCAA Football Week 11 Top 25 Picks
BYU at Texas Tech - Lean Texas Tech
Rising line on Tech at home against undefeated BYU, who won't be able to dominate the line of scrimmage against the Red Raiders in Lubbock.
Texas A&M at Missouri - Opinion: Missouri
Texas A&M (8-0 / 5-0) is off a bye and their best game of the season in destorying LSU in the second half of a 49-25 road win. Plenty of angles against the undefeated Aggies as bettors ride the hot team, but Missouri turns to a 3rd string freshman quarterback and that's where the trends and angles need to be understood and analyzed before blindly betting. Missouri actually has the better defense allowing just 18 points per game and 249 yards per game to A&M 24 ppg and 323 yards per game. Missouri also has a strong, balanced offense averaging 460 yards per game including 238 rushing. Home 'Dog opinion but note back quarterback.
Oregon at Iowa - Opinion: Iowa
Both teams lost to Indiana at home, but Iowa played the Hoosiers tougher than Oregon did. Still, these teams have played four common opponents and the average line was Oregon -13 and Iowa PK 'em. Stats support the Ducks as the strong team by a +3.3 yards per play margin compared to Iowa at +1.1.
Additional games and picks, and check back Saturday for more including stats and information you can bet on.
Indiana at Penn State - Pick: Penn State
I had this as a top pick early week and Playbook Sports notes that undefeated college football road favorites from Game 10 forward are 24-48-1 ATS since 1990 including a bankroll-busting 6-24 ATS as a double-digit favorite when facing a team that allows 23 or fewer points per game. The pressure continues to mount on these teams, and Indiana (9-0 / 6-0) is sitting pretty on top of the Big Ten with Ohio State. But the Hoosiers have never been in such rarified air, and just achieved their highest-ever College Football Playoff ranking. No teams power rating has risen more than Indiana this season, and Penn State (3-5 / 0-5) has seen their power rating fall the furthest. The Nittany Lions lost their starting quarterback and fired head coach Franklin a few weeks ago, and Penn State has failed against the spread (1-7) by more than 80 points while Indiana has buried their opponents by more than 130 points to the spread. Penn State would have been more than a 10 favorite in this matchup at the start of the season making this one of the biggest point spread adjustments you will see.
LSU at Alabama - Addition by subtraction in Baton Rouge with another coach fired in LSU's Brian Kelly? Alabama won 4-straight games against ranked teams starting in late September, but the Crimson Tide have been out-gained in three straight games against Missouri, Tennessee and South Carolina after escaping Columbia last Saturday when the 'Cocks sucked balls and blew it late in a 29-22 'Tide win.
Non-Top 25
San Diego State at Hawaii - Pick: Hawaii
The total has dropped to 48.5 and I played Hawaii (6-3 / 3-2 MW) to take down Mountain West leader San Diego State (7-1 / 4-0) and some strong added angles supporting the Rainbow Warriors as a home 'Dog on the Island.
Our Pick on Tennessee in Week 10 was a loser, but the 33-27 home loss to Oklahoma saw the Vols commit 3 turnovers while outgaining the Sooners 456-331 with a 28-19 first down edge.
Lets hope for better bounces, fortune and results through November and many of the biggest games of the season leading to conference championship games and the College Football Playoff.
College Football Playoff potential and projected matchups and point spreads
Top online sportsbook BetOnline has also released early betting lines for potential College Football Playoff games starting Dec. 19.
- Memphis at Georgia (-21.5)
- Oregon at Texas Tech (pk)
- Virginia at Ole Miss (-15.5)
- Notre Dame (-9) at BYU
Dec. 31 - Jan. 1
CFP Quarterfinals - Cotton Bowl, Orange Bowl, Rose Bowl, Sugar Bowl
- Georgia vs. Alabama (-1)
- Texas Tech vs. Ohio State (-12.5)
- Mississippi vs. Texas A&M (-4)
- BYU vs. Indiana (-12)
- Memphis vs. Alabama (-20)
- Oregon vs. Ohio State (-9.5)
- Virginia vs. Texas A&M (-16.5)
- Notre Dame vs. Indiana (-2)
Two big SEC matchups ahead in Week 12 on Saturday, Nov. 15 with Texas at Georgia and Oklahoma at Alabama. Big game watch and wager action ahead as teams push towards the College Football Playoff, conference championship games, and look forward to the biggest rivarly games over Thanksgiving.
You can bet on it.
FairwayJay is a proven sports handicapper and loves college football. He's been handicapping and betting college football for more than two decades and is recognized as one of the sports industry's most insightful analysts. He chips in additional sports betting coverage and reporting on industry news and events. Follow FairwayJay here at OSGA.com and on X @FairwayJay for more sports and betting insights.
