Predictions and betting advice for Rams vs Bills on MNF
A Week 5 Monday Night Football feature between preseason Super Bowl favorites and All-Pro star quarterbacks should ensure big watch and wager action at top online sportsbooks. The AFC East-leading Buffalo Bills (3-1) tackle the Los Angeles Rams (2-2) at SoFi Stadium with the Rams looking up in the NFC West standings at the undefeated 49ers (5-0) and Seahawks (3-2). 
Check the Monday Night Football preview with information you can bet on.
The Rams have moved from a -3 to -3.5 point favorite since I posted Week 5 picks at Off Shore Gaming Association. The total is up from 53.5 to 54.5 points. I pass on the total and Lean over, but provided an opinion on the Rams as part of our Week 5 picks, props and parlays. NFL spread picks are now 9-2 ATS this season posting at OSGA (opinions (5-6 ATS), and we chipped-in another player prop winner Sunday with another here for Bills-Rams Monday Night Football.
#twitter_embed_1#
The Rams defense has the edge and better stats in 3-of-4 key defensive categories over the Bills - total yards, yards per play, yards per rush and points allowed. Those defensive matchup numbers led us to a 1-0 result on our Week 5 picks on the Steelers. The Rams defense ranks No. 1 so far this season allowing 247 yards per game (Bills 372), No. 2 yards per play at 4.2 (Bills 5.4), and No. 8 in points allowed 20.8 to the Bills 26.8 ppg. The teams are tied in run defense yards per rush at 4.0.
Both the Bills and Rams are Top 8 in rushing offense averaging 139 and 127 yards per game. Bills QB Josh Allen already faces a tough test against the Rams Top 3 defense across the board, and now WR Josh Palmer (shoulder) is out and WR DJ Moore (shoulder) is questionable.
Bet on MNF Football at one of these Elite-rated sportsbooks!
MNF Player Props
Opinion: Rams QB Matthew Stafford over 278.5 passing yards. The number is high, but Stafford has passed for at least 300 yards in three straight games. with two of those against the Broncos and Eagles, following a sluggish start in Australia against the stronger 49ers defense. 
The Bills rank No. 30 in the NFL allowing 256 passing yards per game at 7.5 yards per attempt on 64% completions. Bills opponents have also passed the ball an average of 37 pass attempts per contest, and Stafford has attempted more than 50 passes each of the past two games. Dr. Bob Sports adds that Buffalo ranks #29 in defensive EPA per play and #28 in success rate and they’ve been 4.3 points per game worse than average on that side of the ball after accounting for offensive units faced (adjusted for injuries) and average scoring conditions. Texans QB CJ Stroud passed for 274 yards on 38 attempts against the Bills, and Lions QB Jared Goff passed for 327 on 38 attempts in Buffalo. Then last week, Patriots QB Drake Maye passed for 269 yards on 37 attempts outdoors in Buffalo. Even Chargers QB Justin Herbert passed for 226 yards on 34 attempts at Buffalo with shorthanded receivers and offensive line.
The matchups dictate Stafford will have success again if coach Sean McVay calls for more passes. Bills DT Ed Oliver is out following a knee injury in last week's loss to the Patriots and DL Landon Jackson (knee) is questionable along with CB Dee Alford (ankle).
The Rams look primed to win on Monday Night Football with Stafford continuing his air assault and arsenal of receives led by Puka Nacua and Davante Adams.
You can bet on it.
FairwayJay is a proven sports handicapper with top of the leaderboard success in NFL pointspread prognosis. That includes a 7-year run at OSGA picking 57% ATS winners on only NFL underdogs. FairwayJay is also on the poker and sports scene in Las Vegas covering major sports plus industry conferences, events and football media days. Follow @FairwayJay on X and OSGA for more betting insight and information you can bet on.
