College Football 2022 Top 25 Matchups, Odds And Week 10 Picks

FairwayJay chips a College Football Top 25 Betting Report with Week 10 picks on the biggest games generating the most interest.

Preview and Top 25 Picks for NCAA Football Week 10 

The first College Football Playoff rankings came out this week, and Tennessee is No. 1 followed by No. 2 Georgia. And those two teams meet on Saturday in a huge SEC East division showdown in Athens. This will be one of the biggest bet games of the regular season at the leading online sportsbooks. More than 80% of the early money is on the public underdog Tennessee to cover the spread, which has dropped from Sunday's opener in Las Vegas of Georgia -9 to -8. The over/under is down sharply nearly four points and is currently 66 total points.

You can check out my College Football Playoff Top 25 Picks, Opinions and Leans on the four Top 25 match-ups for Sat., Nov. 5 below. 

- No. 1 Tennessee at No. 3 Georgia | 3:30 p.m. | CBS
- No. 6 Alabama at No. 10 LSU | 7 p.m. | ESPN
- No. 13 Kansas State vs. No. 24 Texas | 7 p.m. | FS1
- No. 21 Wake Forest at No. 22 NC State | 8 p.m. | ACC Network 

College Football Playoff Rankings

Here are the top 10 teams in the current College Football Playoff Rankings

1. Tennessee          6. Alabama
2. Ohio State          7. TCU
3. Georgia              8. Oregon
4. Clemson             9. USC
5. Michigan            10. LSU

Last week I provided the top defensive teams and defensive dominators in college football. Review the list and update the stats as you evaluate the match-ups each week and use these stats as guidelines when handicapping. That includes the more balanced and efficient top offenses

Top 25 Matchups and Picks 

No. 1 Tennessee at No. 3 Georgia | 3:30 p.m. | CBS
Line: Georgia -8 and Total 66 at reduced juice Sportsbook BetAnySports

Additional stats and analysis in my added coverage of the Tennessee-Georgia showdown with the line dipping to Georgia -8. The Bulldogs are a defensive dominator and Georgia's offensive stats are now on par with Tennessee with both teams averaging about 535 yards per game offense vs FBS foes to lead the country. 

Lean: Under

No. 6 Alabama at No. 10 LSU | 7 p.m. | ESPN
Line: Alabama -13 and Total 56.5 at BookMaker

Alabama LSU SEC free pickBoth teams are 4-1 and tied with Ole Miss on top of the SEC West division after LSU crushed the Rebels last week 45-20 with a perfectly balanced 500 yards offense. The Tigers are improved and just played their best game. But Alabama is still the real deal with a defensive dominator defense that stuffs the run and has elite talent on the edge. Junior outside linebacker Will Anderson is a future top-5 NFL Draft pick and has 37 pressures this season. LSU QB Jayden Daniels is a duel threat who leads the Tigers in rushing. But he's been sacked 26 times and will be under more pressure this week. Alabama QB Bryce Young leads the superior team in yards per play (6.9 vs 5.7), and we cashed in on Tennessee with a Pick in the Vols Week 6 blowout win at LSU. The 'Tide can roll as well. 

Opinion: Alabama 

No. 24 Texas at No. 13 Kansas State | 7 p.m. | FS1
Line: Texas -2.5 and Total 54 at BetUS 

Kansas State blew out Oklahoma State last week 48-0, and the Wildcats are now +9 in turnover margin this season. An embarrassing loss for Oklahoma State and our pick on the Cowboys. Texas is rested and ready off a bye week, and the pedigree and potential of the Longhorns is still strong. Texas has played a top 10 schedule and has three close losses, including 20-19 to Alabama earlier this season. The Longhorns also have a stronger yards per play and yards per game margin with both teams on the outer edge of top defenses in our defensive dominator list. 

Pick: Texas 

Wake Forest Top 25 free pickNo. 21 Wake Forest at No. 22 NC State | 8 p.m. | ACC Network
Line: Wake Forest -4 and Total 54.5 at Jazz Sports

NC State freshman QB MJ Morris came off the bench last week to lead the 22-21 comeback win after trailing Virginia Tech 21-3. He passed for 265 yards and 3 Touchdowns. Morris starts this week for injured QB Devin Leary, who had season-ending surgery for a torn pectoral muscle. Wake Forest star QB Sam Hartman threw 3 INT's last week Wake Forest had 8 turnovers in the second half of a 48-21 blowout loss at Louisville. Hartman now has 5 INT's this season with 22 TD passes and continued explosive play potential. 

Lean: Wake Forest

All Top 25 Games on Sat., Nov. 5 

Odds are subject to change and current betting lines from top rated sportsbook BetOnline.

No. 1 Tennessee at No. 3 Georgia (-8.5) | 3:30 p.m. | CBS
No. 2 Ohio State (-38) at Northwestern | 12 p.m. | ABC
No. 4 Clemson (-3.5) at Notre Dame | 7:30 p.m. | NBC/Peacock
No. 5 Michigan (-26) at Rutgers | 7:30 p.m. | Big Ten Network
NCAA football Top 25 predictionsNo. 6 Alabama (-13.5) at No. 10 LSU | 7 p.m. | ESPN
No. 7 TCU (-9.5) vs. Texas Tech | 12 p.m. | FOX
No. 8 Oregon (-31.5) at Colorado | 3:30 p.m. | ESPN
No. 9 USC (-21) vs. Cal | 10:30 p.m. | ESPN
No. 12 UCLA (-10.5) at Arizona State | 10:30 p.m. | FS1
No. 13 Kansas State vs. No. 24 Texas (-2.5) | 7 p.m. | FS1
No. 14 Utah (-17.5) vs. Arizona | 7:30 p.m. | Pac-12 Network
No. 15 Penn State (-14) at Indiana | 3:30 p.m. | ABC
No. 16 Illinois (-17.5) vs. Michigan State | 3:30 p.m. | Big Ten Network
No. 17 North Carolina (-7.5) at Virginia | 12 p.m. | ACC Network
No. 18 Oklahoma State (-2) at Kansas | 3:30 p.m. | FS1
No. 19 Tulane (-7.5) at Tulsa | 12 p.m. | ESPNU
No. 20 Syracuse at Pitt (-3.5) | 3:30 p.m. | ACC Network
No. 21 Wake Forest (-4) at No. 22 NC State | 8 p.m. | ACC Network
No. 23 Oregon State at Washington (-4.5) | 10:30 p.m. | ESPN2 (Friday)
No. 25 UCF (-3.5) at Memphis | 3:30 p.m. | ESPN2

Check back for more college football betting updates and information you can bet on as the biggest games ahead decide conference titles, bowl game spots and a trip to the College Football Playoff for the top four teams. 

You can bet on it. 

FairwayJay is a proven sports handicapper and is recognized as one of the sports industry's most insightful analysts. He chips in additional sports betting coverage and reporting on industry news and events. Follow FairwayJay here at and on Twitter @FairwayJay for more sports and betting insights. 

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